The Rajiv Gandhi Centre for Biotechnology (RGCB) located in Thiruvananthapuram, Kerala, is a pioneering research institution dedicated to cutting-edge biotechnology and molecular biology research. Established in 1990 under the aegis of the Department of Biotechnology, Government of India, RGCB has established itself as a leader in life sciences research. RGCB’s research spans various critical areas including cancer biology, functional genomics, molecular medicine, stem cell biology, infectious diseases, plant biotechnology, and neurobiology. This diverse spectrum of research underscores RGCB’s commitment to addressing pressing scientific questions and real-world challenges. The institute’s state-of-the-art research facilities form the cornerstone of its success. These encompass advanced laboratories equipped with cutting-edge technologies for genomics, proteomics, imaging, structural biology, and more. RGCB houses core facilities for animal research, bioinformatics, and computational biology, fostering interdisciplinary research approaches. Furthermore, RGCB’s collaborative orientation is evident through its partnerships with national and international institutions, universities, and industries, ensuring a globally connected research ecosystem. The institute plays a pivotal role in nurturing the next generation of scientists through its educational programs, workshops, and seminars. In essence, the Rajiv Gandhi Centre for Biotechnology in Thiruvananthapuram serves as a beacon of excellence in biotechnological research. Through its diversified research domains, advanced facilities, and unwavering commitment to innovation, RGCB continues to contribute significantly to scientific advancement and the development of impactful solutions.