SCTIMST Hospital Wing

Home . SCTIMST Hospital Wing

Sree Chitra Tirunal Institute for Medical Sciences and Technology (SCTIMST) stands as an Institution of National Importance in India, operating under the aegis of the Department of Science and Technology, Government of India. The institution’s visionary founders initiated a harmonious fusion of medicine and technology over thirty years ago, a concept that has now matured into a widely embraced paradigm. With university status, SCTIMST offers an exceptional environment for research and training across its three integral components: a specialized tertiary referral hospital, a cutting-edge biomedical technology wing, and the Achutha Menon Centre for Health Science Studies. At the core of its mission, SCTIMST concentrates on delivering advanced and top-tier care for cardiac and neurological ailments, propelling the development of indigenous biomedical technologies, and advancing public health education and research. The institute’s pioneering work spans diverse domains, from interventional radiology and cardiac electrophysiology to innovative medical device creation, culminating in a medical devices incubator (TIMed) and a reputation as a Technical Research Centre for Biomedical devices.

Sl. No. Departments Sub Departments
1
Anaesthesiology Department
  • Cardiothoracic & Vascular Anaesthesiology
  • Neuroanaesthesiology
2
Biochemistry
3
Cardiology Department
  • Adult Cardiology and Interventions
  • Cardiac Electrophysiology
  • Paediatric Cardiology
4
Cardiovascular and Thoracic Surgery Department
5
Cellular and Molecular Cardiology
6
Imaging Sciences and Intervention Radiology Department
7
Microbiology
8
Neurology Department
  • Cognition & Behavioral Neurology
  • Comprehensive Care Centre for Movement Disorders
  • Comprehensive Center for Sleep Disorders
  • Comprehensive Stroke Care Center
  • Multiple Sclerosis and related disorders Division
  • Neuromuscular Division
  • Pediatric Neurology & Neurodevelopmental Disorders
  • R Madhavan Nayar Center for Comprehensive Epilepsy Care
9
Neurosurgery Department
10
Nursing Services
11
Pathology
12
Physical Medicine & Rehabilitation
13
Transfusion Medicine
Sl. No. Area of Research Sub Areas
1
Department of Anesthesiology
  • Intraoperative hemodynamic performance and echocardiographic characteristics
  • Evaluation of Chitra heart valve prosthesis in the aortic and the mitral positions
  • Comparison of effect of isoflurane and sevoflurane on left ventricular diastolic function in patients with ischemic heart disease undergoing CABG
  • Intraoperative changes in pulmonary venous Doppler flow profile before and after surgical closure of atrial and ventricular septal defects.
2
Division of Biochemistry
  • Biochemical basis of diseases such as:
    • Identification of lipoprotein binding serum antibodies and characterization of polysaccharide antibody recognition.
    • Studies on dysfunctional high density lipoprotein (HDL)
    • Developing of a database of young CAD patients in Kerala
  • Experimental and clinical oncology research involving:
    • Insidious role of nitric oxide in tumor cell aggressiveness
    • Studies on characterizing gliomasphere forming cells
    • Mechanisms of natural and synthetic chemical moieties as tentative antitumor agents
3
Department of Cardiology
  • Cardiac electrophysiology in inherited and acquired forms of cardiac dysarrhythmias
  • Functional assessment of coronary lesion in deciding intervention and long term follow up of device closure for cardio defects
  • Community interventions for health: emphasis on calf length and circumference as a marker for adult onset risk factors and diseases
  • Quit Tobacco India Indonesia project: training on behavioral methods at tobacco cessation
4
Department of Cardiovascular and Thoracic Surgery
  • Animal experiments [in pig] with Hydrogel coated large diameter Chitra Vascular graft
  • Implantation of small diameter tissue engineered graft [in sheep].
  • Studies on developing indigenous left ventricular assist device for endstage heart failure
  • Stem cell treatment for patients with ischemic heart disease
  • Preclinical animal trial for stem cell therapy,
  • Preclinical animal trial for modified Chitra heart valve prosthesis
  • Mitochondrial metabolism and function in Type 2 diabetic heart
5
Division of Cellular and Molecular Cardiology
  • Spontaneously hypertensive rat as an experimental model to identify metabolic modulators that prevent and/or regress cardiac hypertrophy.
  • Molecular mechanisms involved in apoptosis resistance, cell cycle progression and collagen expression in cardiac fibroblasts under conditions of ambient stress
  • Effect of oxidative stress and hypertrophy on cardiac stem cells
  • Identification of allelic variants associated with coronary artery disease, hypertension and hypertrophy.
6
Department of Imaging Sciences and Interventional Radiology
  • Development of realtime functional MRI based Brain computer interface for stroke rehabilitation
  • Functional MRI of decision making, multimodality neuroimaging & advanced neuroimaging (fMRI, DTI, EEG correlated fMRI, SWI and perfusion imaging) for better patient management in epilepsy, brain tumors, movement disorders, stroke & dementia.
  • Cerebral vaso-reactivity studies
  • Multimodality evaluation of vulnerability of carotid plaques
  • Cardiac MRI features in hypertrophic cardiomyopathy
  • Development of indigenous stent graft for endovascular aortic aneurysm repair
7
Division of Microbiology
  • Antibiotic resistance mechanisms
  • Surveillance on hospital acquired infections
  • Screening of herbal extracts for Anti bacterial and Anti viral activity
  • Studying possible role of microbial pathogens in causation of non-infectious disorders.
  • Homograft Valve Bank.
8
Department of Neurology
  • Deep Brain Stimulation surgery for Parkinson's disease (PD)
  • Non-motor aspects of Parkinson's disease
  • Motor physiology of Dystonia
  • Pathophysiology and treatment of dyskinesia in PD
  • Role of Alpha-Synuclein and genetics of movement disorders
  • Studies on estimation of serum levels of amyloid-b in patients with Mild Cognitive Impairment (MCI) and Alzheimer's disease (AD)
  • Tau and progranulin levels in patients with Frontotemporal Dementia (FTD)
  • long-term longitudinal study of Cognition in Older Adults in Trivandrum (COAT).
  • Prevalence of sleep disorders in the general population
  • Epworth sleepiness score standardization in Indian population
  • Formulation of new sleep apnea clinical score
  • Contribution of sleep apnea in the progression of CHF, systemic hypertension, isolated pulmonary hypertension, COPD and Type 2 DM
  • Prediabetes and insulin resistance in patients with ischemic stroke and TIA, etiology, risk factors and long term outcome in young stroke patients
  • Natural history of medically treated symptomatic intracranial atherosclerotic disease, prevalence of microbleeds and correlation with stroke subtypes and quality of life of stroke survivors
  • Utilizing DTI with post-ictal diffusivity indices and fractional anisotropy values and DTI tractography to reduce perioperative neurological deficits
  • Development of arterial spin-labeling technique (ASL) and standardize its use in patients with epilepsy to detect the flow changes post ictally.
  • EEG-fMRI studies for identifying the epileptogenic zone in cryptogenic MRI negative focal epilepsies
  • Epilepsy surgery outcome studies.
  • Standard versus selective resective temporal lobe epilepsy surgeries
  • Mortality on long-term following epilepsy surgery
  • Development of standard scores and percentile cut-offs for the scores in relation to verbal and non verbal memory performances in patients with temporal lobe epilepsy (TLE)
  • Allelic, genotypic and haplotypic association in a cohort of pharmacoresistant and pharmacoresponsive patients and normal healthy controls
  • Creation of a database for the pharmacogenomic profile of epilepsy patients from Kerala
  • Studies on stigma, infertility and oxidative stress in women with epilepsy
  • Sero-prevalence of Neurocysticercosis
  • Estimation of autoantibodies to Voltage gated K+ channel in persons with epilepsy
  • Pharmacogenetic study for evaluating the teratogenic effects of anti epileptic drugs
  • The effects of maternal sleep deprivation (restriction) on cognition in the offspring in an animal model.
  • To investigate the role of rapid eye movement (REM) sleep during development in regulation of sexual arousal and erectile events in adult rats.
  • To investigate the effects of acute sleep restriction on sleep and body temperature interactions in different age groups of healthy subjects.
  • To investigate the effects of short- and long-term administration of alpha-asarone on oxidative stress and anxiety alleviation in insomnia model in rats.
  • Scientific evaluation of the sleep-wake altering property of a-asarone, an active principle of Acorus Calamus
9
Department of Neurosurgery
  • Multicentric, multinational, randomized, controlled clinical/surgical trials
  • Preclinical animal evaluation of decellularised bovine pericardium as Dura substitute
10
Department of Pathology
  • Infectious diseases of the central nervous system
  • Tumors of the central nervous system
  • Muscular and neuromuscular diseases
  • Demyelinating diseases, epilepsy and vascular diseases of the central nervous system.
  • Nutritional Cardiovascular Diseases
  • Mucoid Vasculopathy, Atherosclerosis, Metabolic Syndrome, associated Endocrinopathies Diabetes Mellitus, Goitre
  • Low HDL-Cholesterol Dyslipidemia: Human & Primate model
  • Endomyocardial Fibrosis: Human & Primate Model
  • Rheumatic Heart Disease: Pathology and Etiopathogenesis revisited
  • Idiopathic Pulmonary Hemorrhage and non-classical Hermansky Pudlak Syndrome
  • Tumours of the Mediastinum, Chest and Lungs
  • Food & Environmental Toxins, Food & Milk Dysbiosis and Human Health
11
Department of Transfusion Medicine
  • Demographic risk factors associated with undetected hypertension among blood donors of Kerala
  • Patient response to platelet transfusion
  • Red cell antibody screening as a part of research.
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